Bupropion Hydrochloride
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Bupropion Hydrochloride is a prescription medication used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It is also prescribed to help people quit smoking under the brand name Zyban. Unlike other antidepressants, Bupropion works by affecting norepinephrine and dopamine activity in the brain, helping to improve mood, energy levels, and concentration without causing common side effects like weight gain or sexual dysfunction.
Uses of Bupropion Hydrochloride
Bupropion is mainly used to manage depression and prevent depressive episodes during seasonal changes. It is also an effective aid for smoking cessation, reducing cravings and withdrawal symptoms. Some doctors may prescribe it off-label to treat ADHD or to counteract sexual side effects caused by other antidepressants.
Dosage Information
Bupropion Hydrochloride is available in immediate-release, sustained-release (SR), and extended-release (XL) formulations. The typical starting dose for depression is 150 mg once daily, which may increase gradually to 300 mg per day. It should be taken at the same time each day, with or without food. Avoid exceeding the prescribed dose to prevent seizures or other adverse reactions.
Possible Side Effects
Common side effects include dry mouth, insomnia, headache, nausea, dizziness, and increased sweating. Serious side effects like mood changes, hallucinations, or seizures should be reported to a healthcare provider immediately.






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